Isaac was born in Guatemala to a Cuban father and a Guatemalan mother. However he was raised in Miami, Florida. He is also of French and Israeli origins. Before he became an actor, he played lead guitar and sang vocals for his band "The Blinking Underdogs". He graduated from Juilliard School in 2005. Isaac's first major film role was Joseph in the film The Nativity Story. He also had a small role in All About the Benjamins and the Che Guevara biopic Guerrilla. In addition to movie appearances, he made an appearance in the television series Law & Order: Criminal Intent. He also had a part in the movie Body of Lies alongside Leonardo DiCaprio and Russell Crowe.

Filmography

The Jesuit (rumored) (in production) 2012
Steel Town (filming) 2012
Michael Raymond

Cristiada (post-production) 2011
Victoriano 'El Catorce' Ramirez

Ten Year (completed) 2011

W.E (completed) 2011
Evgeni

Drive 2011
Standard Gabriel

Sucker Punch 2011
Blue Jones

Robin Hood 2010
Prince John

Balibo 2009
José Ramos-Horta

Ágora 2009
Orestes

Red de mentiras 2008
Bassam

Che, el argentino 2008
Interpreter (as Óscar Isaac)

La vida ante sus ojos 2007
Marcus

Natividad 2006
Joseph

The Half Life of Timofey Berezin 2006
Shiv

Ley y orden: Acción criminal (TV series) 2006
Robbie Paulson
– The Healer (2006) … Robbie Paulson

Lenny the Wonder Dog 2005
Fartman (as Oscar Isaac Hernandez)

Doble impacto mortal 2002
Francesco

Illtown 1996
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