Paul Shaffer and the World's Most Dangerous Band is an American big band led by Paul Shaffer. It is best known for being David Letterman's house band for 33 years. The band formed in 1982 to serve as house band for NBC's Late Night with David Letterman. When Letterman moved to CBS and began hosting Late Show with David Letterman in 1993, the band added a horn section and second guitarist, renaming itself (due to an intellectual property dispute with NBC) the CBS Orchestra, a name that lasted until Letterman left Late Show in 2015.

After a two-year hiatus, in 2017, the band was revived by Paul Shaffer using its original name, and released an album titled Paul Shaffer & The World's Most Dangerous Band followed by a tour Read more on Last.fm. User-contributed text is available under the Creative Commons By-SA License; additional terms may apply.